Prof. Marius Keel | Swiss Surgery

Dear patients and referring physicians!

Surgery means taking responsibility for a person and is therefore a matter of special trust as well as a question of experience. As a specialist in surgery and orthopedic surgery and traumatology of the musculoskeletal system, I was able to acquire a wealth of experience, thanks in part to international operations.

The special focus of my medical work is on the diagnosis and treatment of injuries and diseases of wear and tear, especially of the hip joint and pelvis. In the case of complicated hip joint fractures, the so-called acetabular fracture, I developed a new minimally invasive surgical approach (pararectus approach according to Keel), which older patients in particular can benefit from.

It is my personal concern to put this experience at the service of the health of my patients.

We warmly welcome patients of all insurance classes!

I am happy to be at your disposal for a personal consultation,

Prof. Marius Keel

Premises of the medical practice spine-pelvis AG

The wife of Prof. Keel is responsible for the design of the premises of “spine-pelvis AG” in the Hirslanden Trauma Center in the Hirslanden Clinic in Zurich. As a lover and passionate collector of Bauhaus architecture, she has been collecting original tubular steel furniture and accessories from this time in various countries for furnishing the practice for over 2 years. A unique environment was created in which diagnoses and therapy options can be discussed in a consultation atmosphere of “different kind”.

Career

since 2020	Swiss Surgery
Since April 2017	Attending physician, Hirslanden Trauma Center, Hirslanden Clinic, Zurich
	Consultant physician (senior consultant) for complex and difficult musculoskeletal interventions, especially pelvic and spine surgery, University Clinic for Orthopedic Surgery and Traumatology, Inselspital, University Hospital Bern, Inselgruppe, Bern (Prof. Dr. KA Siebenrock) </ td >
May 2015 – March 2017	Deputy Clinic Director, Head of Traumatology and Team Leader Pelvic and Spine Surgery, University Clinic for Orthopedic Surgery and Traumatology, Inselspital, University Hospital Bern, Inselgruppe, Bern (Prof. Dr. K.A. Siebenrock)
	Head of Orthopedics and Traumatology, Tiefenau Hospital, Inselgruppe, Bern
September 2012-March 2017	Consultant physician for pelvic, hip and spine surgery, Trauma Center Hirslanden, Hirslanden Clinic, Zurich
August 2012 – April 2015	Deputy Head Physician, Head of Traumatology and Team Leader, Pelvic and Spine Surgery, University Clinic for Orthopedic Surgery and Traumatology, Inselspital, University Hospital Bern (Prof. Dr. K.A. Siebenrock)
November 2010 – July 2012	Head of Traumatology, Team Leader Pelvic and Spine Surgery, University Clinic for Orthopedic Surgery and Traumatology, Inselspital, University Hospital Bern (Prof. Dr. K.A. Siebenrock)
November 2008 – October 2010	Consultant Traumatology, Pelvic and Spine Surgery, University Clinic for Orthopedic Surgery and Traumatology, Inselspital, University Hospital Bern (Prof. Dr. K.A. Siebenrock)
September 2008	Clinical Director, Senior Physician a.i., Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. P. Giovanoli, Clinic Director a.i.)
February 2007 – August 2008	Deputy Clinic Director, Senior Physician a.i., Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. Dr. h.c. O. Trentz)
June 2006 – January 2007	Senior Physician a.i., Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. Dr. h.c. O. Trentz)
September – November 2004	Fellowships – Pelvic and hip reconstruction, Orthopedic Surgery, Good Samaritian Hospital, Los Angeles (Dr. J. Matta)
	Traumatology, Department of Surgery, University of Southern California, LAC + USC Medical Center, Los Angeles (Prof. Dr. D. Demetriades)
January 2003 – May 2006	Senior physician and team leader, Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. Dr. h.c. O. Trentz)
March 2002 – December 2002	Assistent Physician, Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. Dr. h.c. O. Trentz)
March 2001 – February 2002	Senior Physician, Surgical Department, Bülach Hospital (PD Dr. U. Neff and Dr. R. Habegger)
June 1999 – February 2001	Assistant and Senior Physician, Surgical Department, Männedorf District Hospital (Prof. Dr. A. Hollinger and Dr. A. Vollenweider)
January – May 1999	Assistant Physician, Surgical Intensive Care Medicine, University Hospital Zurich (Prof. Dr. R. Stocker)
1995-1998	Assistant Physician, Department of Surgery and Clinic for Trauma Surgery, University Hospital Zurich (Prof. Dr. F. Largiadèr and Prof. Dr. Dr. h.c. O. Trentz)

Milestones

1995 – University of Zurich

Postgraduate course in experimental medicine and biology at the Medical Faculty of the University of Zurich (Fig.1) . The first experimental work was carried out in the laboratory of the Clinic for Trauma Surgery at the University Hospital Zurich.

1995-2008 – Clinic for Trauma Surgery, University Hospital Zurich

Basic research – The work on the reduced immune response, the so-called «endotoxin tolerance» in seriously injured patients, (Fig. 2) and the work on the reduced targeted cell death (« apoptosis ») of immune cells in patients with severe infections (sepsis) (Fig. 3) are considered to be groundbreaking publications. Research on cell death and later on wound healing mechanisms in vacuum-assisted wound therapy was supported by the Swiss National Science Foundation.
The description of the acute phase protein PSP (“Pancreatic Stone Protein”) in severely injured patients with a septic course (Fig. 4) led to a patent (PDF1) . The overview work on the pathophysiological mechanisms (pathological functional disorders) in accident patients (Fig. 5) is still one of the world’s most cited and respected «review» articles in trauma medicine.

Clinical research – In the context of holistic trauma surgery with life-saving and damage-limiting operations, case series and review articles received much international attention (Fig. 6 , Fig. 7) . The first internationally published series of pelvic stabilization with a pelvic clamp and additional cloth tamponades for patients with severe pelvic injuries under resuscitation conditions (Fig. 8) and the largest series of emergency thoracotomies (chest openings for resuscitation and bleeding control) in Europe with one of the world’s best survival rates (Fig. 9) received particular attention.

Another major milestone was participation in the world’s largest prospective randomized study in trauma medicine, in which the influence of blood coagulation factor VII (“Novoseven”) on the use of blood reserves and mortality in severely injured patients with bleeding shock was examined (Fig. 10; «Swiss connection »- article in the study booklet of Novo Nordisk Pharma AG) . However, since the mortality rate in the study was too low, the study was discontinued in 2008, with 541 patients 2.5 years after the start of the study and the most patients in Europe at the Clinic for Trauma Surgery of the University Hospital Zurich under the direction of Prof. Keel (22 Patients). 71 hospitals in Europe, USA, Canada, South America, Oceania, Asia, Africa and Israel participated in the study.

The academic and clinical work of Prof. Keel was honored in 2007 in New Orleans by the American Surgery Society with the admission as a Fellow of the “American College of Surgeons” (Fig. 11a, Fig. 11b, Fig. 11c) .

The constant motivation and inspiration to improve the clinical care of accident victims and also the pathophysiological understanding is to be thanked to Prof. Dr. Dr. h.c. Otmar Trentz, who worked tirelessly like a «Tinguely work of art» as an extraordinary trauma surgeon, teacher and mentor and, as a humanist, was always a great role model for Prof. Keel (Fig. 12; teachers and students in the Tinguely Museum Basel on the occasion of the European trauma and emergency surgery -Congress (ECTES) in Basel 2012) . Unfortunately, when he retired in 2008, Prof. Trentz was refused an appropriate farewell by the University of Zurich and the University Hospital Zurich and the holistic approach of trauma surgery was abandoned in the spirit of specialization. The diploma from Prof. Dr. Dr. h.c. Trentz about Prof. Keel on August 31, 2008 ended with the following honorable words: “Mr. Keel is an“ academic surgeon ”in the best sense of the word. In addition to the acquisition of a high level of clinical competence, he has been extremely committed to research … A retiring boss is proud to say that he has trained and promoted employees in such a way that they are operationally better than the retiring mentor. This applies to Mr. Keel in the best sense. »

Type and date of the surgical / traumatological / orthopedic interventions personally carried out by Prof. Keel for the first time at the Clinic for Trauma Surgery, University Hospital Zurich:

First osteosynthesis (surgical connection of bone fragments) on May 27, 1995
First laparotomy (opening of the abdominal cavity) on December 6th, 1997
First thoracotomy (opening of the chest) on February 19, 1998
First hip prosthesis on July 11, 1999
First spinal stabilization on January 7th, 2003
First pelvic ring osteosynthesis on January 22, 2003
First hip revision prosthesis on April 16, 2003
First acetabulum (hip joint socket) osteosynthesis on June 10, 2003
First surgical hip dislocation to treat an acetabular fracture on January 14, 2004
the world’s first osteochondral transplant on the femoral head on June 18, 2007 (Fig. 13; published case report)

2003 – Habilitation University of Zurich

Awarded his habilitation (private lecturer in surgery) on July 1st, 2003 at the University of Zurich. The title of the habilitation thesis was “Dysregulation of the apoptosis of neutrophil granulocytes – meaning for the immunological “CHAOS” after trauma. This work describes different mechanisms of cell death regulation of immune cells in severely injured patients. The inaugural lecture entitled “The Seriously Injured Man in the Tension Between Specialization and Economics” took place in the full auditorium of the University of Zurich on April 3rd, 2004 (Fig. 14) .